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NADogen®

$83.30
$83.30
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Comprehensive formula helps to maximize NAD+, and support cellular energy.

Benefits

  • Triple Action Formulation: Stimulates NAD+ synthesis through the de novo pathway, the Preiss–Handler pathway, and the salvage pathway.
  • Key Ingredients: Incorporates Nicotinamide Riboside, Pterostilbene, and Tryptophan for maximum efficacy.
  • Boost Cellular Energy: Specifically designed to amplify NAD+ levels, crucial for cellular energy metabolism.
  • Maintaining high NAD+ levels are important for energy production in the cellular mitochondria.
  • Helps to increase NAD+ levels to support healthy production of cellular energy. Helps in energy metabolism and tissue formation.
  • Safe & Sustainable: Uses antioxidant Pterostilbene to enhance Nicotinamide Riboside's capacity to boost NAD+ and awaken the anti-aging gene.
60 vcaps | NPN: 80104492
View Product Details
  • Ingredients
  • Directions & Cautions
  • References
  • Reviews

Ingredients

Medicinal Ingredients

 

Each 2 vegetarian capsules contain:Quantity
Nicotinamide Riboside Chloride284.1 mg
 providing Nicotinamide beta-Riboside (NR)250 mg
D-Ribose314 mg
L-Tryptophan126 mg
Nicotinamide312.5 mg
Pterostilbene120 mg

 

 

Non Medicinal Ingredients

Medium chain tryglycerides (Cocos nucifera) - 100 mg.
Microcrystalline cellulose, ascorbyl palmitate.
Capsule shell: hypromellose (vegan gelatin).

 

Does not contain

GMO ingredients, dairy, egg, gluten, soy, wheat, corn, yeast, nuts, artificial sweeteners, colors or flavors.

Allergen warnings

Coconut

 

Directions & Cautions

Recommended dose

Adults take 2 capsules 1 time per day or as advised by a health care practitioner.

Cautions:

Do not use this product if you are pregnant or breastfeeding. Some people may experience gastrointestinal upset and/or diarrhea. Stop use if hypersensitivity/allergy occurs.

Store in dry, cool place away from sunlight.

Do not use if seal is broken. Keep out of reach of children. Keep sealed, store in a cool, dry place at 15–25ºC.

References

References:

  • Hector Rodriguez Cetina Biefer1 et al., Aspects of Tryptophan and Nicotinamide Adenine Dinucleotide in Immunity: A New Twist in an Old Tale, International Journal of Tryptophan Research  2017 Volume 10: 1–8
  • Ryan W. Dellinger et al. Repeat dose NRPT (nicotinamide riboside and pterostilbene) increases NAD+ levels in humans safely and sustainably: a randomized, double-blind, placebo-controlled study, npj Aging and Mechanisms of Disease (2017)0:17
  • Shin-Ichiro Imai and  Leonard Guarente; t takes two to tango: NAD+ and sirtuins in aging/longevity control; NPJ Aging Mech Dis. 2016 Aug 18;2:16017
  • Na Xie et al,  NAD+ metabolism: pathophysiologic mechanisms and therapeutic potential, Signal Transduction and Targeted Therapy volume 5, Article number: 227 (2020)
  • Bernard Cuenoud et al. Effect of circadian rhythm on NAD and other metabolites in human brain, Frontiers in  Physiology 09 November 2023
  • Daniel C Levine et al.  NAD+ Controls Circadian Reprogramming Through PER2 Nuclear Translocation to Counter Aging, Mol Cell. 2020 June 04; 78(5): 835–849.
  • Daniel C. Levine et al. Circadian NAD(P)(H) cycles in cell metabolism, Seminars in Cell & Developmental Biology Volume 126, June 2022, Pages 15-26
  • Nichola J Conlon, The Role of NAD+ in Regenerative Medicine, Plast Reconstr Surg. 2021 Sep 28;150
  • Tooba Iqbal and  Takashi Nakagawa , The therapeutic perspective of NAD+ precursors in age-related diseases, Biochemical and Biophysical Research Communications, Volume 702, 2 April 2024
  • Sophie Lautrup et al., NAD+ in Brain Aging and Neurodegenerative Disorders, Cell Metab 2019 October 01
  • Shin-ichiro Imai  and Leonard Guarente, NAD+ and sirtuins in aging and disease, Trends in Cell Biology, Volume 24, Issue 8, August 2014,
  • Rashmi Patil and Urmila Aswar, Role of Pterostilbene in Maetabolic Diseass through SIRT1 pathway, Turkish Journal of Agriculture – Food Science and Technology, 2021)
  • Giusy Russomanno et al. The anti-ageing molecule sirt1 mediates beneficial effects of cardiac rehabilitation, Immunity and Ageing , 2017 14:7
  • Amanda J. Stock  and Yie Liu, NAD-Linked Metabolism and Intervention in Short Telomere Syndromes and Murine Models of Telomere Dysfunction, Frontiers in Aging, October 2021, Volumer 2, Article 785171
  • Amanda J. Stock et al. Boosting NAD ameliorates hematopoietic impairment linked to short telomeres in vivo, GeroScience, Volume 45, pages 2213–2228, (2023)
  • Hector Rodriguez Cetina Biefer et al. Aspects of Tryptophan and Nicotinamide Adenine Dinucleotide in Immunity: A New Twist in an Old Tale, Int J Tryptophan Res. 2017 Jun 14

Reviews

Reviews

Discover our innovative solutions expertly crafted to support graceful aging. From brain-boosting supplements to smart wellness formulas, each offering is tailored to enhance mental acuity, promote vitality, and nurture overall well-being to help maintain a sharp mind, strong body, and resilient immune system. By addressing aging at its roots, we empower you to live with clarity, strength, and independence for years to come.