Berberine TPGS™

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For blood sugar levels - Provides support for healthy glucose metabolism.


Highly bio-available berberine in a delay release (DR) vegetarian capsule

Helps to control blood sugar levels

Improves insulin sensitivity

Helps to activate AMP-activated protein kinase (AMPK)

60 DR vcaps | NPN: 80089143
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Berberine TPGS is a well-researched orthomolecular combination of ingredients that provides a significantly higher Berberine coefficient of absorption and utilization.

Berberine is an alkaloid present in several plants such as Goldenseal (Hydrastis canadensis), Oregon grape (Berberis aquifolium), Barberry (Berberis vulgaris) and Chinese Goldthread (Coptis chinensis). Recent and more thorough studies of Berberine were carried out establishing clearly that Berberine has a therapeutic use in metabolic syndrome (MSyn) characterized by high blood sugar and A1c levels. 

Berberine is poorly absorbed across the gut wall and therefore high doses must be taken to achieve therapeutic results. In addition, Berberine is degraded by stomach acids. Berberine TPGS is encapsulated in delay release (DR) capsules to minimize the impact of stomach acids. It also contains a support blend that significantly improves absorption, bio-availability and utilization. Therefore, lower dosages of Berberine are needed but with increased efficacy. This also means less probability for gastrointestinal discomfort.

Berberine TPGS targets to control glucose metabolism in part by activating adenosine monophosphate-activated protein kinase or AMP-activated protein kinase (AMPK) and by increasing expression of insulin receptors and therefore reducing insulin resistance. The activation of AMPK tells the body to burn fats for energy which, by doing so, can also lead to weight loss.

Did you know

High blood sugar is a result of the Metabolic Syndrome and is usually associated with dyslipidemia and increased cardiovascular risk?

Who can benefit?

If you have elevated blood sugar and/or Hemoglobin A1c, Berberine TPGS may help you improve those numbers. However, if you are already taking diabetes medication, you should consult with your healthcare provider prior to use in order to avoid abnormally low blood sugar levels (hypoglycemia).

Recommended dose

Adults take 2 capsule 1 time per day. 
Take without food (preferably take on an empty stomach).

For enhanced control of blood sugar/lipid metabolism it can be associated synergistically with Provita Metabolix™ AMPK.


For use beyond 3 months consult a health care practitioner. Do not use if you are pregnant or breastfeeding. If you have an allergy to seafood, do not use this product. If you have hypoglycemia, hypo-tension or if you take medicines for diabetes, consult a health care practitioner prior to use. If you have leukopenia, consult a health care practitioner prior to use. If you have cardiovascular disease, a liver or kidney disorder or diabetes, consult a health care practitioner prior to use. May cause gastrointestinal discomfort such as constipation, vomiting, abdominal pain or diarrhea, in which case discontinue use and consult a health care practitioner.

Do not use if seal is broken. Keep out of reach of children.

 Keep sealed, store in a cool, dry place at 15–25ºC.

Medicinal Ingredients


Each 2 Delayed Release Vegetarian Capsules Contain:Quantity
Berberine (Berberine hydrochloride)500 mg
Chitosan (deacetylated)33.2 m
Chromium (Chromium picolinate)20 mcg



Non Medicinal Ingredients

Support Blend…216 mg (Caprylic acid, Tocophersolan, Sodium hydroxide)

Microcrystalline cellulose, vegetable stearate, delayed release capsule (hypromellose, gellan gum).

Does not contain

Dairy, egg, gluten, soy, wheat, corn, yeast, nuts, artificial sweeteners, colors, preservatives, or flavors.

Restorative Health

Given the right nutraceutical support, the human body can repair itself and can also restore the immune system to its full capacity. Provita’s continuously evolving Restorative Health series, curated from the highest quality sources, is specially formulated to help the body increase its capacity to repair and restore.