Inflammation is the body's natural defence mechanism, helping to heal injuries and fight infections. However, when inflammation reaches a certain threshold or becomes chronic, it contributes to a range of common health issues, from joint pain and migraines to urinary tract infections and prostate conditions. Left unchecked, persistent inflammation can damage tissues, exacerbate symptoms, and lead to long-term health concerns.
Let’s explore a strategic approach to managing inflammation by pairing Serra-Plus, a powerful, fast-acting anti-inflammatory, with targeted supplements designed to support specific health concerns. This synergistic approach ensures that inflammation is addressed at its root, enhancing the effectiveness of other supplements to provide comprehensive health benefits.
Serra-Plus: A Foundational Anti-Inflammatory
Serra-Plus is designed to combat inflammation at multiple levels, utilizing a blend of potent natural enzymes and extracts. Here are a few highlights:
- Serrapeptase – A proteolytic enzyme that regulates inflammatory cytokines, thereby producing anti-inflammatory effects. Has also been shown to provide analgesic or pain-relieving effects.1
- Curcumin – A polyphenol from turmeric that is well-known for its anti-inflammatory effects.2 It’s combined with piperine in this formula to increase bioavailability.
- Bromelain – This digestive enzyme from pineapple has a long history of use for medicinal purposes in Central & South American cultures. Research shows it promotes the activity of macrophages, lymphocytes, and natural killer cells, which are part of the body’s defence mechanism. Bromelain is also involved in cell signalling pathways related to inflammation.3
- Boswellin 65 – Extracted from a tree, this ingredient has demonstrated effectiveness at reducing pro-inflammatory compounds in the body4
By affecting inflammation, Serra-Plus supports a more balanced internal environment, enhancing the effectiveness of targeted supplements and promoting a holistic approach to health and well-being.
1. Joint Health: Serra-Plus + Arthro-FLX™ Forte
Joint pain and stiffness often stem from inflammation in the cartilage, tendons, and surrounding tissues. Conditions such as arthritis, and general joint wear-and-tear can lead to chronic discomfort, limited mobility, and reduced quality of life. Addressing both inflammation and structural joint health is crucial for long-term relief.
The Comprehensive Approach:
Arthro-FLX™ Forte is specifically formulated with ingredients that support joint function and reduce pain. A few ingredients to highlight:
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Glucosamine & Chondroitin – Essential building blocks of cartilage that are beneficial for maintaining joint structure and mobility.
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Devil’s Claw Extract – This plant has been used for many years in Southern parts of Africa and is well known for its uses in reducing inflammation. Studies indicate it can reduce proinflammatory markers and are effective for managing rheumatoid and osteoarthritis.5
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Hyaluronic Acid – A key component of synovial fluid that lubricates joints and enhances shock absorption.
Pairing Serra-Plus with Arthro-FLX™ Forte is beneficial for managing both the inflammatory response and the structural integrity of the joints, promoting long-term joint health and reducing pain naturally.
2. Headaches & Migraines: Serra-Plus + Migraine Complex
Migraines and chronic headaches are often linked to inflammation in blood vessels, nerve pathways, and surrounding tissues. Triggers such as stress, hormonal changes, and dietary factors can exacerbate inflammation, leading to frequent and debilitating headaches.
The Comprehensive Approach:
Migraine Complex is designed to address the root causes of headaches and migraines with a blend of neurological and vascular-supportive ingredients. It helps prevent and relieve recurring migraine headaches, and helps reduce the severity and frequency of migraine headaches and associated symptoms such as nausea and vomiting, when taken as a prophylactic. And as a prophylactic it can help prevent recurrence of migraines.
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Guarana – Used by Amazonian Tribes for many years, this ingredient contains caffeine which has been studied for its role in managing pain associated with migraines and headaches.6
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White Willow Bark & Feverfew – Studies show the combination of these ingredients reduces migraine frequency and severity thanks to their anti-inflammatory and neuro-modulatory actions in the body.7
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Peppermint Leaf – Peppermint has a long history of use with headaches and migraines. It’s been found to reduce the frequency, duration, and severity of migraines.8
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Yerba Mate Leaf – Containing powerful polyphenols, this tea is common in South America and known for its anti-inflammatory, antibacterial, and antioxidant properties and has a stimulating effect on the central nervous system.9
Combining Serra-Plus with Migraine Complex targets both the inflammatory and neurological components of migraines. This combination may aid in managing acute symptoms and support overall neurological health.
3. Urinary Tract Health: Serra-Plus + UTI Complex
Urinary tract infections (UTIs) are a common health concern, affecting approximately 50% of women at least once in their lifetime. In most cases (85%), UTIs are caused by E. coli bacteria, which travel up the urinary tract and lead to infection.6 The body’s natural inflammatory response to the infection can lead to discomfort, burning sensations, and frequent urination. UTIs can reoccur and continue to affect one's health.
The Comprehensive Approach:
UTI Complex is designed to promote a healthy urinary environment and reduce bacterial overgrowth. It helps prevent the recurrence of urinary tract infections, is fast acting against multi-strain bacteria, and is efficient against E.coli infections. It includes ingredients such as:
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D-Mannose – A naturally occurring sugar that prevents bacteria (especially E. coli) from adhering to the urinary tract wall, reducing the risk of infection.10
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Cranberry Extract – Prevents bacterial colonization and like D-mannose, can deter bacteria from adhering to the urinary tract wall. Cranberry can also reduce the inflammatory cascade that happens as a result of bacterial infection, thereby improving symptoms. Cranberries may also reduce the recurrence of UTIs.11
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Betula Pendula - From the silver birch tree, this ingredient has been used for many years in traditional medicine systems around the world for inflammatory-related ailments, including urinary tract infections.12
Combining Serra-Plus with UTI Complex is beneficial for fighting infection and also reducing the inflammation that contributes to discomfort and recurrence. This duo promotes urinary tract health and overall well-being.
4. Men’s Health: Serra-Plus + Prostate Complex
Prostate inflammation (prostatitis) and benign prostatic hyperplasia (BPH) can lead to urinary issues, discomfort, and long-term complications in men. Symptoms like frequent urination, difficulty starting and stopping urine flow, and pelvic pain are often linked to underlying inflammation in the prostate gland.
The Comprehensive Approach:
Prostate Complex is formulated to support prostate health and reduce inflammation with a blend of clinically studied ingredients:
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Phytosterols – Shown to improve urinary symptoms and flow measures.13
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Saw Palmetto Extract – Blocks the conversion of testosterone into dihydrotestosterone (DHT), a hormone that can promote prostate growth. Reducing DHT levels, it may assist in managing the symptoms of BPH.14
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Graminex® G63 Flower Pollen Extract – A blend of standardized pollen extracts which has been studied for prostatitis. Found to reduce radical oxygen species, and prostaglandins which have a role in regulating inflammation.15
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Pygeum Extract – From the African Prune Tree, this extract has demonstrated effectiveness at reducing nighttime urination and improving urine flow.16
Pairing Serra-Plus with Prostate Complex provides a two-pronged approach: Serra-Plus affects inflammation, and Prostate Complex supports prostate function and urinary health. This combination can alleviate discomfort and support long-term prostate wellness.
Conclusion: A Holistic Approach to Inflammation Management
Chronic inflammation plays a significant role in various health conditions, from joint pain and migraines to urinary and prostate issues. By addressing inflammation at its root with Serra-Plus, Provita’s targeted supplements can work more efficiently, offering a comprehensive and natural approach to long-term wellness.
For those struggling with persistent inflammation-related issues, integrating these targeted combinations into a daily routine can provide lasting relief and improved overall well-being.
Note: Always consult with a healthcare provider before starting any new supplement regimen, especially if you have pre-existing conditions or are taking medications.
References
- Jadhav SB, Shah N, Rathi A, Rathi V, Rathi A. Serratiopeptidase: Insights into the therapeutic applications. Biotechnol Rep. 2020 Oct 17;28:e00544. doi: 10.1016/j.btre.2020.e00544
- Hewlings SJ, Kalman DS. Curcumin: A Review of Its’ Effects on Human Health. Foods. 2017 Oct 22;6(10):92. doi: 10.3390/foods6100092
- Kansakar U, Trimarco V, Manzi MV, Cervi E, Mone P, Santulli G. Exploring the Therapeutic Potential of Bromelain: Applications, Benefits, and Mechanisms. Nutrients. 2024 Jun 28;16(13):2060. doi: 10.3390/nu16132060
- Siddiqui MZ. Boswellia Serrata, A Potential Antiinflammatory Agent: An Overview. Indian J Pharm Sci. 2011 May-Jun;73(3):255–261. doi: 10.4103/0250-474X.93507
- Gxaba N, Coutlyne Manganyi M. The Fight against Infection and Pain: Devil’s Claw (Harpagophytum procumbens) a Rich Source of Anti-Inflammatory Activity: 2011–2022. Molecules. 2022 Jun 6;27(11):3637. doi: 10.3390/molecules27113637
- Boppana SH, Peterson M, Du AL, Simhachalam Kutikuppala LV, Gabriel RA. Caffeine: What Is Its Role in Pain Medicine? Cureus. 2022 Jun 2;14(6):e25603. doi: 10.7759/cureus.25603
- Shrivastava R, Pechadre JC, John GW. Tanacetum parthenium and Salix alba (Mig-RL) combination in migraine prophylaxis: a prospective, open-label study. Clin Drug Investig. 2006;26(5):287-96. doi: 10.2165/00044011-200626050-00006.
- Akhlaghdoust M. The effectiveness of oral peppermint extract on migraine. Anesthesiology and Pain. 2017(7) 1-2.
- Gawron-Gzella A, Chanaj-Kaczmarek J, Cielecka-Piontek J. Yerba Mate - A Long but Current History. Nutrients. 2021 Oct 21;13(11):3706. doi: 10.3390/nu13113706
- Ala-Jaakola R, Laitila A, Ouwehand AC, Lehtoranta L. Role of D-mannose in urinary tract infections – a narrative review. Nutr J. 2022 Mar 22;21:18. doi: 10.1186/s12937-022-00769-x
- Mantzorou M, Giaginis C. Cranberry Consumption Against Urinary Tract Infections: Clinical State- of- the-Art and Future Perspectives. Curr Pharm Biotechnol. 2018;19(13):1049-1063. doi: 10.2174/1389201020666181206104129
- Rastogi S, Mohan Pandey M, Kumar Singh Rawat A. Medicinal plants of the genus Betula—Traditional uses and a phytochemical–pharmacological review. J Ethnopharmacol. 2014 Nov 18;159:62–83. doi: 10.1016/j.jep.2014.11.010
- Wilt TJ, Ishani A, MacDonald R, Stark G, Mulrow CD, Lau J. Beta‐sitosterols for benign prostatic hyperplasia. Cochrane Database Syst Rev. 1999 Jul 26;1999(3):CD001043. doi: 10.1002/14651858.CD001043
- Kwon Y. Use of saw palmetto (serenoa repens) extract for benign prostatic hyperplasia. Food Sci Biotechnol. 2019 Apr 17;28(6):1599–1606. doi: 10.1007/s10068-019-00605-9
- Locatelli M, et al. Graminex Pollen: Phenolic Pattern, Colorimetric Analysis and Protective Effects in Immortalized Prostate Cells (PC3) and Rat Prostate Challenged with LPS. Molecules. 2018 May 11;23(5):1145. doi: 10.3390/molecules23051145
- Wilt TJ, Ishani A. Pygeum africanum for benign prostatic hyperplasia. Cochrane Database Syst Rev. 1998 Jan 26;1998(1):CD001044. doi: 10.1002/14651858.CD001044