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Synergistic Indole-3-Carbinol

Helps to support and promote healthy estrogen metabolism and balance.


  • Support & promote healthy estrogen

  • Support metabolic balance

  • Synergistic added DIM (Di-indolylmethane)

  • High potency formula

30 vcaps | NPN: 80059133

  • Vegan stamp
  • Non GMO stamp
  • Gluten free stamp
  • Soy free stamp
  • Dairy free stamp
  • GMP stamp
  • Canadian stamp

What is it

Recent studies show that Indole-3-carbinol (I-3-C) offers powerful antioxidant properties particularly beneficial for women. Extracted from cruciferous vegetables such as kale, broccoli, brussels sprouts, cabbage, and bok-choi, I-3-C has proven to support safer estrogen metabolism and reduce the associated risks. 

Provita’s Synergistic Indole-3-Carbinol, includes Di-indolylmethane (DIM) which works synergistically to promote healthy estrogen levels in women and men.

DIM is a stable indole also found in cruciferous vegetables. DIM promotes beneficial estrogen metabolism and helps to reduce the severity and duration of symptoms associated with recurrent breast pain (cyclical mastalgia).

Did you know

I-3-C is produced by the breakdown of the glucosinolate glucobrassicin, which can be found at relatively high levels in cruciferous vegetables such as broccoli, cabbage, cauliflower,
brussels sprouts, collard greens and kale.

What is in it

Medicinal Ingredients

Each Vegetarian Capsule Contains:

Indole-3-Carbinol 200 mg
DIM (3,3’-Di-indolymethane) 25 mg
Isolated from Brassica species    

Non Medicinal Ingredients

Microcrystalline cellulose, vegetable stearate.    
Capsule shell: hypromellose (plant gelatin).    

Does not contain

Dairy, egg, gluten, soy, wheat, corn, yeast, nuts, artificial sweeteners, colors, preservatives, or flavors.

Who should take it

Who can benefit?

Indole-3-Carbinol can be used for a range of health issues. It can be helpful in balancing hormonal levels, assisting in detoxification or just as a general health booster.

Recommended dose

Adults take 1 capsule 1 to 2 times per day.


Consult your health care provider prior to use if you are taking any medication or natural health products, have a liver disorder or symptoms of low estrogen (such as joint pain, mood changes, changes in libido, hot flashes, night sweats, vaginal dryness or irregular menstruation). If you develop liver-related symptoms (e.g. abdominal pain, jaundice) or symptoms of low estrogen, discontinue use and consult a health care practitioner. To exclude the diagnosis of a serious cause of hormonal imbalance, consult a health care practitioner prior to use. Do not use if you are pregnant or breastfeeding.

Do not use if seal is broken. Keep out of reach of children. Keep sealed, store in a cool, dry place at 15–25ºC.

Leave a review!

  1. Jo  · 

    As long as Provita keeps making “Synergistic Indole 3 Carbinol formula… I am a loyal customer! Thanks for all you Provita!

  2. Gi  · 

    As a male, I rely on this supplement to help decrease chances of developing cancer… prevention is a must! As cancer runs in my family, I3C is a must for me & I would not go a day without it! I would rather go without my cell phone & without my laptop… but not without this product!

    Provtia I3C is my holy grail!